Can insulin injections cause insomnia? A patient’s attendant asked me this question:
“My father is unable to sleep whenever we give him insulin. Can you please guide me if there’s something wrong with the insulin or if it could be something else? He can’t sleep even when his blood sugar is normal after taking insulin.”
This is the first time someone asked me this question. I was unaware of how to answer this patient’s question.
But one logical answer was if insulin was causing hypoglycemia resulting in adrenaline release – adrenergic symptoms of hypoglycemia.
Adrenaline is a stimulant drug and hypoglycemia could be triggering adrenaline release which then causes insomnia.
However, whether or not insulin directly disrupts your sleep is not known. If you are on insulin, please answer the poll at the end of the post.
Sleep is crucial for overall health, and disruptions can be distressing for both the patient and the family. Let’s explore whether insulin could be the culprit and other possible explanations for this issue.
Read: Trouble Falling Asleep with Ozempic and Mounjaro: Tips for a Sound Sleep
Could Insulin Be Causing Sleep Problems?
Insulin is a lifesaving treatment for people with diabetes, but it’s not commonly known to directly affect sleep.
However, there are scenarios where insulin or factors related to its administration might indirectly cause sleep disturbances:
- Hypoglycemia (Low Blood Sugar):
Insulin lowers blood sugar levels, and if the dose is too high or meals are skipped, blood sugar might drop too low during the night.
Symptoms of hypoglycemia, such as sweating, shaking, restlessness, or even nightmares, can disrupt sleep. However, in the case described, the patient’s blood sugar was normal, so hypoglycemia might not be the cause.
Type and Timing of Insulin:
Long-acting or intermediate-acting insulins are typically designed to maintain steady blood sugar levels. However, if a rapid-acting insulin is used close to bedtime, it might cause fluctuations that make the patient feel uncomfortable or restless.
Pain or Discomfort from Injection:
If the insulin is injected right before bedtime, the discomfort or pain from the injection itself might disrupt the process of falling asleep. This disruption can be particularly problematic if the patient struggles to return to sleep after being woken.
Tolerance to Sleep Medications:
If the patient has been on long-term sleep medications, they may have developed a tolerance, reducing the medications’ effectiveness. Insulin administration might further disrupt an already fragile sleep pattern.
Potential Medication Interactions:
Review all medications, including sleep aids, with the treating physician to rule out potential interactions with insulin or other treatments.
Read: Rybelsus and Insomnia: Is Rybelsus Disrupting Your Sleep?
Other Possible Explanations for Sleeplessness
If insulin isn’t directly responsible, other factors might be at play. Here are some possibilities to consider:
Diabetic Neuropathy:
Many people with diabetes develop nerve damage, especially in the hands and feet. This can lead to sensations of pain, tingling, or burning at night, which can make it difficult to sleep.
Stress and Anxiety:
Managing diabetes, particularly with injections, can cause stress for both patients and their families. Anxiety about the disease itself, fear of hypoglycemia, or apprehension about the injection can make it harder to relax and fall asleep.
Sleep Apnea:
Obstructive sleep apnea is more common in people with diabetes and can significantly disrupt sleep. Symptoms include snoring, gasping for air, or daytime fatigue.
Restless Leg Syndrome (RLS):
RLS is a condition that causes uncomfortable sensations in the legs, particularly at night. It’s also more common in people with diabetes and could explain difficulty sleeping.
Other Underlying Conditions:
Pain from arthritis, gastrointestinal discomfort, or other unrelated health conditions could also interfere with sleep.
What Can Be Done? Suggestions and Solutions
If your father is experiencing sleeplessness after taking insulin, here are steps you can take to address the issue:
Monitor Blood Sugar Levels:
Use a continuous glucose monitor (CGM) or check blood sugar levels during the night to rule out unnoticed fluctuations.
Discuss Insulin Type and Dosage:
Speak with the treating physician about the type of insulin being used and its timing. Adjustments in dosage or switching to a different insulin formulation might help.
Address Pain or Discomfort:
If the timing of the injection coincides with bedtime, consider administering insulin earlier in the evening to avoid disrupting sleep. Applying a cold compress to the injection site might also help reduce discomfort.
Evaluate Sleep Medication Use:
If the patient has been on sleep medications for a long time, discuss with the healthcare provider whether tolerance has developed. A change in medication or dose adjustment might be necessary.
Evaluate for Sleep Disorders:
If sleep apnea or restless leg syndrome is a possibility, consult a sleep specialist for evaluation and management.
Review All Medications:
Work with the treating physician to review all current medications, including sleep aids, to ensure there are no potential interactions with insulin.
Promote Relaxation:
Encourage relaxation techniques such as deep breathing, meditation, or a warm bath before bed to reduce stress and anxiety.
Ensure Comfortable Sleep Environment:
Optimize the bedroom for sleep by maintaining a cool, quiet, and dark environment.
Conclusion:
Insulin itself is unlikely to directly cause sleep problems, but it can contribute indirectly through mechanisms like hypoglycemia, discomfort from injections, or disruptions in routine.
Additionally, long-term use of sleep medications may reduce their effectiveness, making it harder to recover from interrupted sleep.
It’s also possible that other factors, such as neuropathy, stress, or sleep disorders, are at play.
The best course of action is to consult a healthcare provider for a thorough evaluation. With the right adjustments and support, your father can hopefully enjoy restful nights again.
Please answer the poll to see the effects of insulin on sleep:
- Question of
Do you or your loved one experience sleep issues after taking insulin?
- Yes, frequently (more than 3 times a week)
- Occasionally (once or twice a week)
- Rarely (less than once a month)
- No, never
- Question of
When does the sleeplessness usually occur in relation to insulin administration?
- Immediately after the injection
- A few hours later
- No specific time pattern
- Not applicable (no sleep issues)
- Question of
Which is the most distressing symptoms after insulin administration?
- Restless and agitation
- Physical discomfort or pain at the injection site
- Anxiety about blood sugar levels (hypoglycemia)
- Symptoms of low blood glucose (sweating, hunger, shaking)
- None of the above
- Question of
Are there any additional factors that might contribute to sleep disturbances in your case?
- Abnormal sleep habits (going to bed very late)
- Abnormal dietary habits (take caffeinated beverages at night)
- Other health issues (shortness of breath, restless legs syndrome)
- Pain (Arthritis, body pain, neuropathic symptoms like tingling and burning)
- None
- Question of
Have you tried anything to improve your sleep?
- Yes, I have changed my insulin type
- Yes, I have changed (reduced) my insulin dose
- Yes, I have changed my insulin timings
- Yes, I have started taking sleeping pills
- Yes, I have changed my diet and started taking supplements
- No