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Dupixent Before and After Pictures: Dupilumab for Eczema

Dupixent Eczema Before and After Pictures

Dupixent before and after eczema pictures: Reviews and pictures of patients with atopic dermatitis or eczema that were successfully treated with Dupixent (Dupilumab) are presented here.

The reviews and pictures of patients with eczema are taken from Reddit/Eczema.

Patients who posted their before and after pictures of eczema treatment with Dupixent posted pictures of various parts of their body, primarily the:

  • face
  • eyes
  • hands
  • finger
  • tummy
  • neck

A brief overview of Dupixent (Dupilumab):

Dupilumab is a biological medicine prepared by recombinant DNA technology. It is marketed by the brand name Dupixent Injection.

The injection is administered once every two weeks into the skin via a prefilled syringe or injection.

It acts by inhibiting the action of two important cytokines, IL-4 and IL-13. Both these cytokines are involved in the differentiation of Th2 cells.

Inhibiting these cytokines ultimately inhibits the release of chemicals from cells involved in allergic and inflammatory processes.

Dupilumab (Dupixent) may be used in combination with topical corticosteroids. Dupixent may also be used in combination with topical calcineurin inhibitors like Pimecrolimus (Elidel).

The combination of topical Elidel treatment and Dupixent injection is usually reserved for patients who have involvement of the face, genitals, groin, eyes, or armpits.

These skin areas are considered hard-to-treat areas.

Dupixent Before and After Pictures of the Face: Facial Eczema:

The face is considered a hard-to-treat skin area because one can not use high-potency topical corticosteroids on the face.

Before Dupixent, these patients were treated with a low-potency corticosteroid in combination with a calcineurin inhibitor like Elidel cream (Pimecrolimus).

However, Dupixent has changed the treatment of these hard-to-treat areas altogether.

Facial eczema and Eczema around the eyes cleared with Dupixent
Facial eczema and Eczema around the eyes cleared with Dupixent

Dupixent Review of the patient:

“I took this picture when my flare-up was at its worst. I still can not forget the pain and agony. I felt like I was falling apart.”

“I believe that Dupixent might not be effective for all and some patients might not get it because of the cost and insurance issues. I feel sorry for you if you are one of them”.

But, don’t give up hope and keep trying different medicines as one day you might find an effective medicine that helps you.”


Facial Eczema: Before treatment, Picture and after six months of Dupixent:

As mentioned earlier, the face is one of the most difficult to treat areas. More importantly, you can not hide it. It is associated with so much stigma if you have a diseased face compared to the rest of your body.

A slight improvement in facial appearance is linked with so much confidence and energy. Hence, I selected this picture of a patient who was successfully treated with Dupixent.

Here are the pictures after six months of Dupixent injection use:

 

Facial eczema cleared with Dupixent use after 6 months
Facial eczema cleared with Dupixent use after 6 months

Dupixent worked like a miracle. This picture was taken after six months of Dupilumab injection.

Dupixent Reviews of the patient:

“Dupixent has been a game-changer for me. I am so thankful.”

“This is incredible. I finally feel like myself.”


Six months of treatment using Dupixent: Before and after treatment pictures of legs and tummy:

These are pictures of the same patient who had facial atopic dermatitis and got huge relief using Dupixent for six months.

Although skin involvement other than the face, groin, genitals, and armpits can be treated with topical corticosteroids, extensive application of topical corticosteroids has its own cons.

Prolonged use of topical corticosteroids over extensive skin surfaces is associated with Cushing syndrome.

These patients may develop diabetes, hypertension, osteoporosis, fungal infections, and cushingoid facies.

Dupixent might help in reducing the dose of corticosteroids required to treat extensive skin disease.

Tummy eczema cleared with Dupixent use
Tummy eczema cleared with Dupixent use

The above picture is before Dupixent (Dupilumab) use, while the lower picture is after six months of using Dupilumab Injection. There is marked interval improvement.

Below are the tummy pictures of the same patient from the sides. Again, there is marked improvement as seen in the pictures shown here.

Tummy side views Dupixent before and after
Tummy side views of Dupixent before and after

The same patient also shared pictures of her arms. Below are the pictures of her arms before and after treatment. The skin seems smooth and very healthy.

Eczema on the arms cleared with Dupixent: Above picture is before Dupixent use and the lower picture is after Dupixent use.
Eczema on the arms cleared with Dupixent: The Above picture is before Dupixent use and the lower picture is after Dupixent use.

Lastly, pictures of her legs and feet. All the rashes disappeared within six months of Dupixent use. The skin is very healthy now.

Limb eczema after 6 months of Dupixent
Limb eczema after 6 months of Dupixent

Review of the patient:

“I feel like myself, finally. It feels so incredible. I am so thankful.”


Dupixent Reviews: Eczema of the arms cleared after only three shots!

Although Dupixent may take up to 16 weeks, the time to reach a steady-state concentration, some patients notice improvement after the first few shots.

This is a review of a patient who noticed a marked improvement in the symptoms of his arm and forearm eczema.

Dupixent before and after pictures of eczema on the arms
Dupixent before and after pictures of eczema on the arms

This patient had a rapid improvement in his eczema. He noticed improvement only after three shots of Dupixent injection.

Patient Reviews:

“I am getting my life and confidence back.”

Dupixent use and Random Flares on the neck and chest:

Random flares have been observed in patients who initially responded very well. Random flares have been observe,d especially in skin areas that are located around the eyes and near the face.

This is a picture of a patient who observed random flares in her symptoms after she got rid of a huge amount of eczema on her torso.

After months of using Dupixent, she started observing random flares over her neck and chest. Although mild, but is still something to be worried about because the face and surrounding areas are very important as far as looks are concerned.

Dupixent Side effects Red Face DFR
Dupixent cleared eczema but developed random flares on chest and neck

Dupixent cleared this patient’s eczema, but she developed random flares.

Reviews of the patient:

“I need help. I need to manage this. I got rid of huge amounts of eczema on my torso within a few weeks of starting Dupixent treatment, but noticed random flares over my chest and neck”.

Three months on Dupixent: Eczema of the hands and arms:

This is another patient who used to wear long sleeves just to hide his hands and forearms. He has shared pictures of his hand and forearm after three months of using Dupixent.

Dupixent Before and after pictures of hands
Dupixent Before and after pictures of hands

Review:

After three months of Dupixent, I can finally feel some sort of normal. I used to wear long sleeves to hide all the rashes and scabs on my forearms.

Facial Eczema Cleared with Dupixent but flared with Aquaphor:

This patient used Dupixent for four months. After she noticed flares, especially over her face, she consulted her dermatologist.

Her facial eczema actually flared after she started using Aquaphor. Aquaphor is a cosmetic cream used OTC for skin dryness.

Her skin condition rapidly improved when she stopped using Aquaphor.

dupixent after 4 months
Dupixent use after 4 months

Reviews:

I thought Dupixent wasn’t helping me when my face turned red after four months of using Dupixent. Turned out Aquaphor was the reason for my flares. I was using it like crazy. No flares after quitting Aquaphor.

 Facial Eczema: Dupixent Before and After Pictures:

Another patient had severe eczema of the face that resolved almost completely using only four months of Dupixent treatment.

The facial skin cleared of all the scabs, extra skin, and redness, and became healthier.

Before Dupixent use picture
Face before Dupixent use
Face eczema cleared after Dupixent use
Face eczema cleared after Dupixent use

Reviews about Dupixent use:

“What a difference this made in my life. Now my skin feels more elastic and healthy. I strongly recommend those who are on the fence about starting Dupixent treatment.”

Dyshidrotic Eczema cleared with Dupixent:

Dyshidrotic eczema or pompholyx is basically an eczema of the palms and soles. Since the skin of the palms and soles is very thick, it is difficult to treat using topical corticosteroids.

Dupixent injection has helped this patient change his hand appearance significantly. he stated that his hand eczema cleared after struggling for 17 years and he had lost all hope.

dyshidrotic eczema clearing with Dupixent
Dyshidrotic eczema clearing with Dupixent

Dupixent Reviews:

“Dupixent changed my life. I look back at my life and want to cry some days. I have had dyshidrotic eczema involving my hands for about 17 years, and I never thought my hands would look normal again.”

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What do you think?

Written by Dr. Ahmed

MBBS, FCPS (Medicine) | Assistant Professor of Medicine
Internal Medicine Specialist | Chronic Disease & Wellness Expert | Medical Writer

I am Dr. Ahmed Farhan, a board-certified Internist with over 15 years of clinical experience at Pakistan Institute of Medical Sciences, Islamabad, one of the busiest tertiary-care hospitals in Pakistan. I specialize in chronic disease management, diabetes care, obesity treatment, nutrition, and lifestyle medicine.

For the past 6–7 years, I’ve been writing evidence-based health articles on Dibesity.com and Emedz.net, helping thousands of readers make informed decisions about their health.

My medical writing follows international standards (ICMJE), and I ensure every article is:

Scientifically accurate
Up-to-date with the latest guidelines & research
Easy to understand for patients and families

Outside of medicine, I enjoy morning walks, hiking, nature, and spending quality time with my three daughters.

📌 Learn more about my qualifications and background → About Me
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